Hyalorib - Ophthalmic gel for dry eye -

HYALORIB


Hyposmolar ophthalmic gel for dry eye syndrome

Hyposmolar gel for dry eye syndrome based on Hyalorib, the new chemical entity developed by SERVImed. Indicated for Dry Eye (mild to severe) and patients with a need for lubrication and reduction of oxidative stress on the ocular surface. 

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Hyalorib - Ophthalmic gel for dry eye -

HYPOSMOLAR OPHTHALMIC GEL


For Dry Eye Syndrome

Hyposmolar gel for dry eye syndrome based on Hyalorib, the new chemical entity developed by SERVImed. Indicated for Dry Eye (mild to severe) and patients with a need for lubrication and reduction of oxidative stress on the ocular surface. Preservative and emulsifier free.

 

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HYALORIB

New Chemical Entity

  •  New Hyaluronic Acid
  •  Colored and transparent
  •  High stability

Hyalorib mechanically anchors itself to the microvilli of the epithelial cells; its unique structure allows for more cross-linked molecules, increasing the volume and stability of the tear film. This promotes the restoration of the mucous layer of the tear film, trophism, and the regeneration of the epithelial layer in case of insult from pathogenic agents.

HOW IT WORKS

Action mechanism

 

Lubricates and protects: Hyalorib lubricates the cornea and conjunctiva and performs a nourishing, protective, and antioxidant action against external environmental insults.

Renews the lipid phase of the tear film: At each instillation, it creates a protective "jacket" that replenishes and renews the lipid phase of the tear film, preventing premature evaporation and destabilization of the tear as occurs in the dysfunction of the Meibomian gland. Vitamin E TPGS is capable of creating amphiphilic micellar structures. This allows the ophthalmic solution to promote the natural restoration of the altered lipid layer in dry eye syndromes due to Meibomian gland dysfunction. In addition, it can form micellar structures and promotes the anchoring of hyaluronic acid to the receptors of the ocular surface, contributing to the natural restoration of the mucous layer of the tear film.

Rebalances tear osmolarity: The hypotonicity of the solution allows to restore the balance of the hyperosmolar tear present in dry eye syndrome.

ADVANTAGES

 

New Hyaluronic Acid 

  • Hyalorib associated with Vitamin E TPGS
  • Protective effect
  • Colored and transparent
  • More stable than other formulations
  • Longer permanence on the eye (3-4 hours)
  • Visible under the slit lamp’s blue light

Hyposmolar

  • The hypotonicity of the solution allows for restoration of the hyperosmolar tear balance in dry eye syndrome
  • Improved distribution and increased persistence of the solution on the ocular surface

Easy and comfortable application

  • The gel is applied like a normal eye drop, it spreads in a few seconds creating a protective layer that stabilizes the tear film, counteracting the premature evaporation of the tear itself
  • The solution is well-tolerated, maintains the same refractive index as the tear, and does not alter vision